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Among those who have already received the vaccine, fewer than 0.1% developed a light fever, and about two people per million developed "relative serious adverse reactions" such as allergies, according to Zeng. You may opt-out by. SINGAPORE - When asked if they would take the Covid-19 jab once it hits the market, some well-known Singaporeans had mixed views. Several companies already had vaccine platforms targeting other coronaviruses such as MERS and SARS. The company is likely to have data on whether its vaccine works or not by this month, and has noted that it would seek emergency approval from the FDA if the vaccine is at least 70% effective. Other major vaccine makers including Oxford-AstraZeneca, Moderna, and Novavax have also signed deals to provide Japan hundreds of millions of doses in total. Some countries like the United States and United Kingdom have already begun vaccinating priority groups and the public. (related: How Will The Covid-19 Vaccine Impact Moderna’s EPS?) • In Singapore, the Expert Committee on Immunisation (ECI) recommends the HPV vaccination for females aged nine to 26 years old. A health official prepares a vaccine kit during a Covid-19 vaccine mock drill in Chennai on January 2. While Moderna intends to produce between 500 million to 1 billion doses of its vaccine over 2021, it has no real manufacturing track record and has never produced or sold a commercial drug to date. In fact, we think that the strong data from the vaccine – which is developed using messenger RNA (mRNA) technology could actually mean a lot more for Moderna (NASDAQ: MRNA), another Covid-19 vaccine player, whose entire drug pipeline is based on mRNA technology. The stock is down by about -7.6% this year. Meanwhile, Russia has signed agreements with four Indian manufacturers to produce about 300 million doses of the Russian-developed Sputnik V vaccine, according to Russian, China approved its first homegrown coronavirus vaccine for general public use. The stock is up 253% this year. Overall, Moderna’s vaccine could offer the best of both worlds – high effectiveness and easier logistics, although it could be slightly more difficult to manufacture compared to Pfizer’s. [1] Lonza is also producing the vaccine in the U.S. at its New Hampshire facility. Arcturus (Nasdaq: ARCT) hopes the compound will prove effective as a vaccine against SARS-CoV-2, the virus that causes COVID-19. Opinions expressed by Forbes Contributors are their own. Mr Gan said Singapore is expecting more Covid-19 vaccine deliveries in the next few months, including from US biotechnology firm Moderna and China's Sinovac. On Thursday, December 24, 2020, in Dublin, Ireland. With ongoing trials in more than a dozen countries, China will be sending out hundreds of millions of doses in the coming months. This is positive news, considering that Moderna has no real manufacturing track record and has never produced or sold a commercial drug prior to the Covid-19 shot. in the U.S., and by ROVI and Recipharm outside the U.S. See our indicative theme of  Covid-19 Vaccine stocks which includes U.S.-listed pharma and biotech companies. SII is allowed to produce the Oxford-AstraZeneca vaccine for use within India, but the government has barred them for export until at least March or April -- meaning other countries may have to source their Oxford-AstraZeneca doses from other production sites. The strong efficacy and the speed at which the vaccine was developed should essentially reduce the perceived risk surrounding the rest of Moderna’s pipeline of 21 vaccines and therapies for rare diseases. While Moderna’s stock trades at about $150 per share, its valuation still looks reasonable at about 25x our projected 2020 EPS. Firstly, the efficacy compares favorably with Pfizer’s Covid vaccine, which reported efficacy of 90%. A coolroom at Singapore's Changi Airport, preparing for the arrival of its first shipment of Pfizer-BioNTech vaccines, on December 16, 2020. While Moderna has a Covid vaccine of its own in the works, with efficacy data expected any time now, the strong response of Pfizer’s mRNA bodes well not just for Moderna’s Covid efforts, but also for the rest of the company’s sizable pipeline which is focused mostly on vaccines and therapies for rare diseases. The country is also working to secure deals with American companies. 6. The US pharmaceutical company and its German partner announced earlier last month that final results from its vaccine trial showed that it is 95 per cent effective . [12/10/2020] Can Moderna Rise To The Manufacturing Challenge? Not so fast: analysts, After Admitting Mistake, AstraZeneca Faces Difficult Questions About Its Vaccine. The stock has more than doubled over the last month as the company began publishing efficacy data. novartis singapore pharmaceutical manufacturing Novartis was created in 1996 through the merger of Ciba-Geigy and Sandoz and has a rich history spanning over 200 years. Pfizer’s vaccine could also face logistical issues, considering that the vaccine needs to be stored at a temperature of minus 94 degrees Fahrenheit. SINGAPORE, Dec 21 — Singapore received its first shipment of Covid-19 vaccine this evening on board a Singapore Airlines (SIA) cargo flight from Belgium, where it was manufactured. While Pfizer‘s (NYSE: PFE) surprisingly strong initial Covid-19 vaccine efficacy readout likely marks the beginning of the end of the Covid-19 pandemic, it probably doesn’t mean too much for Pfizer stock, given the limited potential profits and challenges with distribution. Firstly, supply will remain an issue in the near-term. Although the number could change as more data comes in, it is nevertheless indicative of a highly effective vaccine. [1] The companies … As we’ve said before, Moderna’s Covid-19 vaccine is likely to emerge as the most sought-after vaccine in developed markets, considering its stellar efficacy rates and relative ease of storage. The country will also receive 2 million doses of the Sinovac vaccine in three batches, delivered in February, March and April. Now the initial data from Pfizer and its German partner BioNtech’s Covid-19 vaccine appears to confirm this, with the vaccine’s efficacy standing at 90% based on initial data, versus the U.S. FDA’s baseline efficacy requirement of just 50% for the approval for Covid-19 vaccines. Most countries in Southeast Asia have not approved vaccines yet -- but nearly all have signed deals to receive China's vaccine candidates, as well as signing additional deals with other providers. While there are two other vaccines by drug majors Pfizer and AstraZeneca that have reported phase 3 results, it looks like Moderna’s vaccine offers the best balance of efficacy and ease of storage and distribution. Switzerland-based Lonza, one of the world’s largest pharmaceutical services companies, will produce the key mRNA active ingredient for the vaccine in New Hampshire and Switzerland. Japan ranks "among the countries with the lowest vaccine confidence in the world," according to a recent study by The Lancet. Being a clinical-stage biotech, Moderna also lacks the sophisticated supply chain of big pharma companies such as Pfizer and Johnson & Johnson. For instance, the company Shenzhen Kangtai Biological Products has already. Singapore will begin its voluntary vaccination starting with the Pfizer-BioNTech vaccine, which has been approved by the Health Sciences Authority (HSA) for usage here. Moderna’s Cytomegalovirus (CMV) vaccine, which is currently in phase 2 studies and could move to phase 3 in 2021, is likely to be the company’s first candidate for approval after its Covid-19 vaccine. Chinese leaders have promised a growing list of developing countries priority access to its successful vaccines. This might include you though you may have invested money in these companies, or may have been working with one of them for years as an employee, or have consulted with them as an expert for a long time. Surprisingly, the founders of Trefis discovered that along with most other people they just did not understand even the seemingly familiar companies around them: Apple, Google, Coca Cola, Walmart, GE, Ford, Gap, and others. The company has 21 programs underway, around 13 of which are in the clinical stage. The company already has supply agreements with the U.S., Canada, Japan, the U.K., Israel, Qatar, and Switzerland and is also having discussions with several other countries. See their vaccine plan, China's Sinopharm says its Covid-19 vaccine is 79% effective, China approves Sinopharm Covid-19 vaccine, promises free shots for all citizens, New Zealand commits to travel bubbles with Australia, Cook Islands. (related: How Will The Covid-19 Vaccine Impact Moderna’s EPS?) While most vaccine stocks declined last week, amid a broader sell-off in the markets, they are likely to come back into the spotlight as efficacy data from late-stage trials is expected from frontrunners Pfizer (NYSE: PFE) and Moderna (NASDAQ: MRNA) in the coming weeks. The Pfizer-BioNTech vaccine is expected to approved by Australian regulators by the end of January, Morrison said. [3]. Called Lunar-Cov19, the vaccine is developed by Duke-NUS Medical School and American pharmaceutical company Arcturus Therapeutics. [2], Moderna is working with multiple partners to produce its vaccine. The Pfizer-BioNTech vaccine arrived at Changi Airport aboard a scheduled SIA Boeing 747-400 freighter service from the Belgian capital Brussels at about 7.35pm. Here’s a high-quality portfolio to beat the market, with about 120% return since 2016, versus about 60% for the S&P 500. Over 500 employees based in Singapore are dedicated to empowering the lives of patients all over the world. On the other hand, vaccines being developed by the likes of Oxford- AstraZeneca, Novavax, and others can be held at regular refrigerated temperatures. The Vaccine Business Unit based in Singapore hosts a laboratory for analytics and development of vaccines to protect against important infectious diseases in the region. Separately, Swiss regulators have reportedly allowed Moderna’s contract manufacturer Lonza Group to start producing its Covid-19 vaccine at a plant in Switzerland, which will apparently have a capacity to produce 800,000 doses a day. On top of this, vaccine manufacturers are required to … Chinese Premier Li Keqiang said some Southeast Asian countries would be given priority, including Cambodia, Laos, Myanmar, Thailand and Vietnam. NSA Will Install Trump Loyalist Michael Ellis As Its General Counsel, Stocks This Week: Sell Short General Dynamics And Transocean, Fauci Warns Of ‘Ominous’ New Covid-19 Strains, Says Biden Can Achieve Aggressive Goal Of Vaccinating 100 Million In 100 Days, January’s Message: 2021 Is Not 2020. Considering that the vaccine is co-developed with BioNTech, any profits will likely be shared. Moderna indicates that it could have about 20 million doses of its vaccine ready by this year and expects to produce between 500 million to 1 billion doses next year in collaboration with Switzerland-based Lonza. Singapore is in talks with major suppliers of COVID-19 vaccines on the possibility of being a regional distributor and playing a part in the final stages of vaccine production, Trade and Industry Minister Chan Chun Sing said on Monday. Is this jump warranted? No Choosing Of Vaccines. The vaccine was over 94% effective in preventing Covid-19 and 100% effective in preventing severe cases of infection – meaning that no one who received the vaccine developed a serve case of the infection. MSD manufactures medicines and vaccines that are sold in more than 140 countries. But the emergency-use approval comes with restrictions on global distribution. On Thursday, December 24, 2020, in Dublin, Ireland. SINGAPORE has made arrangements with various pharmaceutical companies to facilitate their clinical trials and drug development in Singapore, with the government having attracted a few players to establish vaccine manufacturing capabilities here. | Takeda. We think it largely is, but there are some risks as well. (related: A Look At Moderna’s Pipeline Beyond The Covid Vaccine). Competition is also likely to mount as there are likely to be several more successful vaccine candidates from other companies in the coming quarters. The country is still evaluating other candidates, including China's. As well as global, regional and local commercial operations, we have a significant manufacturing presence in Singapore, comprising two global manufacturing supply sites and a vaccines manufacturing facility. The companies are on track to file an emergency use application with the U.S. FDA later this month if pending data indicates that the vaccine is safe. The stock is down by -5.1% this year. The vaccine will also be the first to seek emergency use approval from the FDA. (CNN)One year after the Covid-19 outbreak began, countries around the world are racing to secure and distribute vaccines to their citizens. The company also said that it was continuing to invest and add staff to potentially produce as much as 1 billion doses for the full year. However, there are a couple of factors that could help the company scale up quickly. [Updated 12/1/2020]Moderna (NASDAQ Large parts of the rich … Johnson & Johnson (JNJ): Unlike most other vaccine candidates, which are likely to require two shots, J&J is targeting a single-dose vaccine. Germany’s CordenPharma will produce the lipids – which are used to deliver the mRNA. India, second only to the US in the number of coronavirus cases worldwide. The Southeast Asian carrier is in talks with some of the vaccine manufacturers, and working out details of the planned trials, according to The … The central government will cover the cost, allowing residents to receive the vaccine. In a recent poll by NHK, 36% of respondents didn't want to take a Covid-19 vaccine. There are still some concerns though. Led by MIT engineers and Wall Street analysts, Trefis (through its dashboards platform dashboards.trefis.com) helps you understand how a company's products, that you touch, read, or hear about everyday, impact its stock price. So how is the company going to meet demand? Secondly, Moderna’s vaccine should be easier to distribute compared to Pfizer’s, as it can likely be stored at refrigerator-like temperatures for 30 days, unlike Pfizer’s vaccine which requires much colder temperatures of around -94 degrees Fahrenheit – limiting its use to more developed parts of the world. Moderna’s Covid-19 vaccine could emerge as the most sought-after vaccine, particularly in developed markets – considering the high levels of efficacy as well as manageable refrigeration requirements, unlike Pfizer’s candidate which is also highly effective but needs to be stored at ultra-cold temperatures. CTLT Updated 0231 GMT (1031 HKT) January 9, 2021. Janssen vaccinations could start in the second quarter, and Pfizer vaccines will arrive in the third quarter, according to Prime Minister Chung Sye-kyun. That being said, some hiccups are to be expected as the company works with a tight timeline. It did not disclose where the AstraZeneca vaccine would be produced. Data sources: Biotechnology Innovation Organizati… Following are all of the companies that are actively developing COVID-19 vaccines either on their own or in partnership with another drugmaker. (Related: Are Covid Vaccine Stocks Worth Investing In?) How Will The Covid-19 Vaccine Impact Moderna’s EPS? The vaccine will be free of charge, with a goal to vaccinate 50 million people ahead of February's Lunar New Year celebrations. See our indicative theme of  Covid-19 Vaccine stocks – which includes U.S.-listed pharma and biotech companies. STRONG MANUFACTURING PRESENCE IN SINGAPORE. The two vaccines: The Serum Institute of India (SII) has been manufacturing the vaccine developed by Oxford University and AstraZeneca. Pharmaniaga is ready to efficiently distribute Covid-19 vaccines as soon as it receives the go-ahead from the government. According to the Hong Kong government, the Sinovac vaccine will be made in Beijing, but the Pfizer-BioNTech vaccine will come from Europe. Once the vaccine is produced, the fill-finish operation – which is the process of filling vials and packaging the vaccine for distribution – is handled by Catalent [6] There could be challenges in areas such as Immuno-Oncology as well, where Moderna is betting big. © 2021 Forbes Media LLC. Some would … Most other countries are still waiting on local regulators to approve vaccine candidates before they can roll out inoculation programs -- and in the meantime, are scrambling to sign deals with pharmaceutical companies to buy the coveted doses in advance. Gan added that vaccine recipients will also be observed on-site for 30 minutes after receiving their vaccination, so that any severe allergic reactions such as anaphylaxis can be detected and promptly treated. Japanese Prime Minister Yoshihide Suga at a press conference in Tokyo on January 4. Moreover, the mRNA technology that Moderna (and Pfizer) are using requires specialized manufacturing equipment. [5] The speed and the efficacy of the Covid vaccine also indicate that Moderna could leverage this technology to develop new lines of vaccines against a variety of viruses. [7] Moderna’s vaccine offers an efficacy that’s similar to Pfizer’s and can apparently be stored at refrigerator-like temperatures for 30 days. There is a lot of competition in the race for a Covid-19 vaccine, and it’s likely that there will be multiple successful candidates from other companies. See our indicative theme of  Covid-19 Vaccine stocks – which includes U.S.-listed pharma and biotech companies. [1] The companies intend to manufacture up to 50 million doses this year, and as much as 1.3 billion doses in 2021. The platform uses extensive data to show in a single snapshot what drives the value of a company's business. Arcturus Therapeutics announced on Dec. 28 that it received approval from the Singapore Health Sciences Authority to proceed with a Phase 2 clinical study of its vaccine candidate ARCT-021, also known as LUNAR-COV19. All Rights Reserved, This is a BETA experience. The Oxford-AstraZeneca vaccine could be approved in February. The vaccines will be funded by the government and given to priority groups first, including medical workers, military members, the elderly, those with severe diseases, and essential personnel. Singapore: The first batch of volunteers aged between 21 and 55 in Singapore have received a dose of a potential coronavirus vaccine being developed in the country. Sanofi. The theme is up by about 540% year-to-date versus about 10% for the S&P 500. The stock has soared 2,000% year-to-date. Japan has not yet approved any vaccine, and has faced criticism over its slowness to act as cases reach new daily highs, prompting leaders to declare a state of emergency for the capital Tokyo in January. Investors cheered the news, sending Moderna stock up by about 20% on Monday’s trading. There are a couple of reasons why Moderna’s vaccine is much sought after. For perspective, the Covid-19 vaccine was apparently designed within a few days. Unlike traditional vaccines which use a virus protein that needs to be grown over the course of weeks, mRNA molecules – which instruct the body to produce virus proteins by itself – are less complex and are produced via a chemical process (rather than a biological process) making mass production much quicker. [Updated 11/10/2020] What Does Pfizer’s Vaccine Readout Mean For Its Stock?Pfizer (NYSE: PFE) and its German partner BioNTech indicated that their Coronavirus vaccine, dubbed BNT162b2, was over 90% effective at preventing Covid-19 infections among volunteers, based on early data from phase 3 trials. — Bernama pic. Can Senate Handle Trump’s Impeachment And A New Stimulus Package At Once? Comprised of companies with strong revenue growth, healthy profits, lots of cash, and low risk, it has outperformed the broader market year after year, consistently. Takeda Vaccines Pte. By the end of March, four million people should have been vaccinated, according to Prime Minister Scott Morrison. The results are surprisingly strong, considering that the U.S. FDA had set a baseline efficacy of just 50% for the approval for Covid-19 vaccines. That’s below the S&P 500 that trades at about 26x projected earnings. For example, not all viruses are similar to Covid, which mRNA might be better at mimicking. Here's what we know about Covid-19 vaccines in Asia Pacific. Our indicative theme of Covid-19 Vaccine stocks – which includes a diverse set of U.S.-based pharma and biotech companies developing Covid vaccines – is up by about 560% year-to-date, on an equally weighted basis, compared to the S&P 500 which has gained just about 4% over the same period. Singapore is home to Sanofi’s regional headquarters, local head office, manufacturing facility as well as regional export center. Here’s Why, China’s Rare Earths ‘Slump’ A Sign Of Domestic ‘Hoarding’ For EV Batteries, And More, The Flawed Inflation Narrative; And “V” vs. “U”, It’s Been A Numbers Game For Netflix And Investors Want To See How They All Added Up. [Updated 11/4/2020] Covid-19 Vaccine stocks. : MRNA) published final results from its 30,000-person phase 3 trial of its Covid-19 vaccine and indicated that it would apply for emergency use authorization with the U.S. FDA. CAMBRIDGE, Mass.--(BUSINESS WIRE)--Dec. 14, 2020-- Moderna, Inc., (Nasdaq: MRNA) a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients, today confirmed that the Company concluded an agreement with the Ministry of Health of Singapore to supply mRNA-1273, Moderna’s vaccine … Below is a bit more on the companies in our theme of Coronavirus Vaccine stocks and their relative performance. The vaccines will be free for the public, Widodo said in December. What if you’re looking for a more balanced portfolio instead? [11/27/2020] What’s Happening With Moderna Stock?Moderna (NASDAQ: MRNA) stock rallied by over 10% on Wednesday’s trading after the European Union agreed to buy 80 million doses of its Covid-19 vaccine, with an option to buy up an additional 80 million doses. See our indicative theme of  Covid-19 Vaccine stocks – which includes U.S.-listed pharma and biotech companies. [Updated 11/11/2020] Why Pfizer’s Vaccine Data Is Good News For Moderna. ), More importantly for Moderna investors, the vaccine’s results also bode well for the rest of the company’s pipeline, which is entirely based on mRNA technology which has never been used previously in commercial drugs. See all Trefis Price Estimates and Download Trefis Data here, What’s behind Trefis? See How It’s Powering New Collaboration and What-Ifs For CFOs and Finance Teams | Product, R&D, and Marketing Teams, Led by MIT engineers and Wall Street analysts, Trefis (through its dashboards platform dashboards.trefis.com) helps you understand how a company's products, that you. The theme is up by about 877% year-to-date versus about 14% for the S&P 500. mRNA offers significant flexibility with vaccine and potentially drug development. The company has received about $1.6 billion in funding from the Federal government. Once the genetic code of a virus is available, Moderna essentially adapts messenger RNA to trigger the immune system to produce protective antibodies without using the actual part of the virus, unlike traditional vaccines. Once a large percentage of the global population is vaccinated (likely by 2022 or 2023) the earnings potential of the Covid vaccine will diminish. [4] However, it should be noted that sales of the vaccine will be significantly front-loaded. India has authorized two Covid-19 vaccines for use, putting its enormous vaccine-manufacturing capacity in the spotlight. He added that they are working to move up the Pfizer vaccine, to potentially the second quarter. No estimate was given for Novavax. Novartis provides healthcare solutions that improve and extend people’s lives. The companies are on track to file an emergency use application with the U.S. FDA later this month if pending data indicates that the vaccine is safe. AstraZeneca’s vaccine, on the other hand, faces concerns regarding some gaps in its trial data, which could undermine its reported results. high-quality portfolio to beat the market, Lonza gets Swiss OK to start Moderna vaccine production -paper, How mRNA vaccines from Pfizer and Moderna work, Moderna’s Covid-19 vaccine was designed in just two days, Pfizer-BioNTech COVID-19 vaccine data ‘open the floodgates’ for mRNA in infectious disease. This enabled them to rapidly prototype experimental vaccines for immunizing against the novel coronavirus that causes COVID-19. That said, Moderna’s success with Covid doesn’t guarantee that its vaccines and therapeutics in other areas, such as cancer, will be as effective. Down by about 721 % year-to-date versus about 10 % for the s P. Mrna technology that Moderna ( and Pfizer ) are using requires specialized manufacturing equipment following are all the... One type of Covid-19 vaccine Impact Moderna ’ s EPS each year over 2021 and.! 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